A Rare Case of Hemophagocytic Lymphohistiocytosis Associated With Myelodysplastic Syndrome and Trisomy 8 in a Pediatric PatientKim, Seh Hyun, MD; Yi, Dae Yong, MD; Lee, Na Mi, MD; Yun, Sin Weon, MD; Chae, Soo Ahn, MD; Lim, In Seok, MDJournal of Pediatric Hematology/Oncology: January 2019 - Volume 41 - Issue 1 - p e57–e59 doi: 10.1097/MPH.0000000000001174 Online Articles: Clinical and Laboratory Observations Abstract Author InformationAuthors Article MetricsMetrics Hemophagocytic lymphohistiocytosis (HLH) is a rare disease resulting in clinical and biochemical manifestations of extreme inflammation. Myelodysplastic syndrome (MDS) represents a heterogenous group of clonal hematopoietic disorders. The development of MDS is common in children with trisomy of chromosome 8. Here, we report a fatal case of 8-year-old girl who was admitted to the emergency department with status epilepticus, and later diagnosed with HLH associated with MDS and trisomy of chromosome 8. We believe this is the first reported case of HLH associated with MDS and trisomy 8 in a pediatric patient. Department of Pediatrics, Chung-Ang University College of Medicine, Seoul, Korea The authors declare no conflict of interest. Reprints: Soo Ahn Chae, MD, Department of Pediatrics, Chung-Ang University Hospital, 102, Heukseok-ro, Dongjak-gu, Seoul 06973, Korea (e-mail: email@example.com). Received June 27, 2017 Accepted February 28, 2018 Copyright © 2019 Wolters Kluwer Health, Inc. All rights reserved.