Institutional members access full text with Ovid®

Share this article on:

An Adolescent With a Rare Midline Neck Tumor: Thyroid Carcinoma in a Thyroglossal Duct Cyst

Vassilatou, Evangeline MD, PhD; Proikas, Konstantinos MD; Margari, Niki MD, PhD; Papadimitriou, Nikolaos MD, PhD; Hadjidakis, Dimitrios MD, PhD; Dimitriadis, George MD, PhD

Journal of Pediatric Hematology/Oncology: July 2014 - Volume 36 - Issue 5 - p 407–409
doi: 10.1097/MPH.0000000000000113
Clinical and Laboratory Observations

Occurrence of malignancy in a thyroglossal duct cyst (TDC) in children and adolescents is very rare, preoperative diagnosis is a challenge, and appropriate management is still debated. We report a 19-year-old male patient referred for a midline neck mass diagnosed as an atypical TDC after initial and subsequent investigations. Ultrasound-guided fine-needle aspiration (FNA) of the mass was diagnostic for papillary thyroid carcinoma. Sistrunk procedure and total thyroidectomy were performed. Histologic analysis confirmed the presence of papillary thyroid carcinoma within TDC, infiltrating surrounding soft tissues. Postoperatively, radioiodine ablation treatment was administered, followed by TSH suppression therapy.

Supplemental Digital Content is available in the text.

*Endocrine Unit

§2nd Department of Internal Medicine—Propaedeutic

2nd Department of Otorhinolaryngology

Department of Cytopathology, Athens University Medical School, “Attikon” University Hospital, Athens, Greece

Supplemental Digital Content is available for this article. Direct URL citations appear in the printed text and are provided in the HTML and PDF versions of this article on the journal's Website,

The authors declare no conflict of interest.

Reprints: Evangeline Vassilatou, MD, PhD, Endocrine Unit, 2nd Department of Internal Medicine—Propaedeutic, Athens University Medical School, “Attikon” University Hospital, 1 Rimini st., Haidari, Athens 12462, Greece (e-mail:

Received March 18, 2013

Accepted January 8, 2014

Copyright © 2014 Wolters Kluwer Health, Inc. All rights reserved.