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Pancytopenia After Allogeneic Bone Marrow Transplant Due to Copper Deficiency

Hudspeth, Michelle MD; Turner, Amy BSN; Miller, Nicole MD; Lazarchick, John MD

Journal of Pediatric Hematology/Oncology: May 2014 - Volume 36 - Issue 4 - p 316–318
doi: 10.1097/MPH.0b013e318290c644
Clinical and Laboratory Observations

Pancytopenia occurring 1 year or later after allogeneic bone marrow transplantation typically prompts a primary consideration for relapse. We present the case of a 15-year old-girl who underwent transplantation for therapy-related myelodysplasia secondary to Ewing sarcoma treatment who developed pancytopenia with myelodysplasia 1 year after transplant due to copper deficiency. Copper deficiency is an important consideration in the evaluation of pancytopenia and myelodysplasia in pediatric patients.

*Department of Pediatrics, Division of Pediatric Hematology/Oncology

College of Medicine

Department of Pathology, Medical University of South Carolina, Charleston, SC

The authors declare no conflict of interest.

Reprints: Michelle Hudspeth, MD, Department of Pediatrics, Division of Pediatric Hematology/Oncology, Medical University of South Carolina, 135 Rutledge Ave., MSC 558, Charleston, SC 29425 (e-mail:

Received October 1, 2012

Accepted March 2, 2013

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