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Dermatopathic Lymphadenitis Associated With Human Papilloma Virus Infection and Verruca Vulgaris

Acipayam, Can MD; Kupeli, Serhan MD, MSc; Sezgin, Gulay MD; Acikalin, Arbil MD; Ozkan, Ayse MD; İnan, Defne Ay MD; Bayram, İbrahim MD; Tanyeli, Atila MD

Journal of Pediatric Hematology/Oncology: May 2014 - Volume 36 - Issue 4 - p e231–e233
doi: 10.1097/MPH.0b013e3182913e44
Online Articles: Clinical and Laboratory Observations

Here we present a pediatric case of human papilloma virus associated with dermatopathic lymphadenitis (DL). A 5-year-old boy presented to the pediatric oncology clinic with swelling of the neck and warts on his lower jaw. His blood chemistry and complete blood count were normal, as was chest x-ray. HIV, EBV, CMV, and parvovirus serologies were negative. The patient was investigated for malignancy and lymphoma but no association was found. Histopathologic examination of the lymph node and the lesion revealed DL and verruca vulgaris, respectively. DL represents a benign form of reactive lymph node hyperplasia and described in patients with HIV and EBV infections. It is a rare entity described in patients with human papilloma virus infection. To our knowledge, this is the first report of DL in a patient with human papilloma virus infection.

*Division of Pediatric Oncology/BMT Unit

Department of Pathology, Cukurova University Medical School, Adana, Turkey

The authors declare no conflict of interest.

Reprints: Can Acipayam, MD, Division of Pediatric Oncology/BMT Unit, Cukurova University Medical School, Balcali 01330, Adana, Turkey (e-mail:

Received August 31, 2012

Accepted February 24, 2013

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