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Spontaneous Rupture of the Spleen in a Patient With Systemic Lupus Erythematosus Initially Presented as Evans Syndrome

Tokgoz, Huseyin MD; Caliskan, Umran MD; Atas, Bulent MD; Ozbek, Orhan MD; Tavil, Betul MD

Journal of Pediatric Hematology/Oncology: January 2014 - Volume 36 - Issue 1 - p e39–e41
doi: 10.1097/MPH.0b013e3182816074
Online Articles: Clinical and Laboratory Observations

Background: Although splenic abnormalities are common in patients with lupus, spontaneous rupture of spleen is extremely rare.

Observations: A 15-year-old boy with new-onset Evans syndrome subsequently diagnosed as systemic lupus erythematosus developed spontaneous rupture of spleen during the course of his illness. Despite the severe thrombocytopenia, he was managed conservatively with gradual regression of hematoma without further complication.

Conclusions: Splenic rupture may occur spontaneously in the course of systemic lupus erythematosus. We conclude that conservative treatment of splenic rupture may be preferred especially in immunocompromised patients to avoid surgical complications.

Departments of *Pediatric Hematology

Pediatric Nephrology

Radiology, Konya University Meram Faculty of Medicine, Konya

§Ankara Children’s Hematology and Oncology Hospital, Ankara, Turkey

The authors declare no conflict of interest.

Reprints: Huseyin Tokgoz, MD, Department of Pediatric Hematology, Konya University Meram Faculty of Medicine, Akyokus mevkii, Meram-Konya 42080, Turkey (e mail:

Received March 28, 2012

Accepted December 4, 2012

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