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Regression of Mesenchymal Hamartoma of the Liver With Sarcoma Chemotherapy

Kuperman, Amir A. MD; Kornreich, Liora MD; Feinmesser, Meora MD; Ash, Shifra MD; Yaniv, Issac MD; Cohen, Ian J. MB, ChB

Journal of Pediatric Hematology/Oncology: January 2013 - Volume 35 - Issue 1 - p e25–e26
doi: 10.1097/MPH.0b013e3182667ba6
Online Articles: Clinical and Laboratory Observations

We present a young patient with metastatic Ewing sarcoma that had hepatic lesions. As we were unaware of hepatic metastases in Ewing sarcoma, liver biopsy was performed. The pathologic findings were diagnostic of mesenchymal hamartoma of the liver. Surprisingly, the combined chemotherapy for metastatic sarcoma resulted in almost complete resolution of the hamartoma in the liver. This option may be useful in extreme cases when resection is not feasible.

*Pediatric Hematology and Blood Coagulation Service, Western Galilee Hospital, Naharia

Faculty of Medicine in the Galilee, Bar-Ilan University, Safed

Department of Pediatric Imaging, Schneider Children’s Medical Center of Israel, Beilinson Medical Campus

§Department of Pathology, Rabin Medical Center

Department of Pediatric Hematology-Oncology, Schneider Children’s Medical Center of Israel, Petah Tikva, Israel

The authors declare no conflict of interest.

Reprints: Amir A. Kuperman, MD, Pediatric Hematology and coagulation service, Western Galilee Hospital, P.O.Box 21, Naharia 22100, Israel (e-mail:

Received November 1, 2011

Accepted June 25, 2012

Copyright © 2013 Wolters Kluwer Health, Inc. All rights reserved.