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Current Practice Managements Regarding Thromboembolic Prophylaxis Within the Pediatric Sarcoma Patient Population

Crocco, Lauren MD; Gorlick, Richard MD; Geller, David S. MD

Journal of Pediatric Hematology/Oncology: January 2013 - Volume 35 - Issue 1 - p 28–31
doi: 10.1097/MPH.0b013e318266bf72
Original Articles

Objective: Children with cancer are approximately 600 times more likely to develop thromboses than the general pediatric population. Current management strategies for children have been extrapolated from adult studies and prophylaxis guidelines remain controversial. The purpose of this study is to survey the current thromboembolic prophylaxis practice methods of physicians treating pediatric sarcoma patients.

Methods: Physicians involved in the care of sarcoma patients were surveyed using a 5-question survey designed to evaluate current clinical practices.

Results: Of 107 responding physicians, 67 identified themselves as involved in the treatment of pediatric sarcoma patients. The providers most likely to use any form of deep vein thrombosis prophylaxis were orthopedic surgeons (60%), followed by general surgeons (45%), pediatric oncologists (30%), and medical oncologists (25%). Of the providers polled, 48% use mechanical forms, 20% use chemical forms, and 31% use a combination.

Conclusions: Currently, there is a lack of consensus regarding thromboembolic prophylaxis for pediatric sarcoma patients.

Departments of *Orthopaedic Surgery

Pediatrics and Molecular Pharmacology, Montefiore Medical Center, The Albert Einstein College of Medicine, Yeshiva University, Children’s Hospital, Montefiore, Bronx, NY

Supported by the Swim Across America Foundation, Foster Foundation, and Cure Search Foundation.

The authors declare no conflict of interest.

Reprints: David S. Geller, MD, Department of Orthopaedic Surgery, Montefiore Medical Center, The Albert Einstein College of Medicine, Yeshiva University, 3400 Bainbridge Avenue, Bronx, NY 10467 (e-mail

Received September 18, 2011

Accepted June 26, 2012

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