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Late-onset Blueberry Muffin Lesions Following Recombinant Erythropoietin Administration in a Premature Infant

Pandey, Vishal MD; Dummula, Krishna MD, MPH; Fraga, Garth MD; Parimi, Prabhu MD

Journal of Pediatric Hematology/Oncology: October 2012 - Volume 34 - Issue 7 - p 534–535
doi: 10.1097/MPH.0b013e3182678f1e
Clinical and Laboratory Observations

Recombinant erythropoietin is being used in premature population for anemia of prematurity. It is considered very safe in this population, although risks are still being evaluated. We report the first case of dermal erythropoiesis as a side effect of recombinant erythropoietin in an extremely prematurely born infant presenting with late-onset blueberry muffin lesions.

Departments of *Pediatrics, Division of Neonatology

Pathology, University of Kansas, School of Medicine

Neonatal Intensive Care Unit

§Department of Pathology and Laboratory Medicine, University of Kansas Hospital, Kansas City, KS

The authors declare no conflict of interest.

Reprints: Vishal Pandey, MD, 3901 Rainbow Blvd, Wescoe 3037A, Mail Stop: 2030, Kansas City, KS 66160 (e-mail:

Received September 20, 2011

Accepted June 26, 2012

Copyright © 2012 Wolters Kluwer Health, Inc. All rights reserved.