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Pure Red Cell Aplasia Associated With Cytomegalovirus Infection

Kumar, Vishal MD*; Gupta, Shalu MD*; Singh, Smita MD; Goyal, Vishnu K. MD*; Yadav, Mukesh MD*

Journal of Pediatric Hematology/Oncology: May 2010 - Volume 32 - Issue 4 - p 315-316
doi: 10.1097/MPH.0b013e3181cb4383
Clinical and Laboratory Observations

A 3-month-old boy presented with progressive pallor since the age of 1 month. Hemogram and bone marrow aspirate were suggestive of pure red cell aplasia. Serum bilirubin and aminotransferases were elevated. Cytomegalovirus serology and DNA polymerase chain reaction were positive. Fetal hemoglobin was normal and Parvovirus B19 DNA polymerase chain reaction was negative. Through this case report, we wish to highlight a rare, might be causative association of cytomegalovirus infection with pure red cell aplasia.

*Department of Pediatrics, Chacha Nehru Bal Chikitsalya

Department of Pathology, Lady Hardinge Medical College, New Delhi

Reprints: Vishal Kumar, MD, Chacha Nehru Bal Chikitsalya, Geeta Colony, New Delhi-110031 (e-mail:

Received for publication September 14, 2009; accepted November 15, 2009

© 2010 Lippincott Williams & Wilkins, Inc.