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Congenital Solid Thigh Mass: A Report of Nonself Healing Form of Langerhans Cell Histiocytosis

Küpeli, Serhan MD, MSc*; Varan, Ali MD*; Ayvaz, Mehmet MD; Ruacan, Şevket MD; Büyükpamukçu, Münevver MD*

Journal of Pediatric Hematology/Oncology: May 2010 - Volume 32 - Issue 4 - p 312-314
doi: 10.1097/MPH.0b013e3181c80bdf
Clinical and Laboratory Observations

Langerhans cell histiocytosis (LCH) is very rarely seen in the pediatric age group. Self-healing is the usual clinical course in congenital LCH with cutaneous involvement. We describe a newborn with a solid mass in his thigh noticed at birth, without skin manifestations. LCH should be considered in the differential diagnosis of congenital solid masses.

*Department of Pediatric Oncology, Institute of Oncology

Departments of Orthopedics and Traumatology

Pathology, Faculty of Medicine, Hacettepe University, Ankara, Turkey

Reprints: Serhan Küpeli, MD, MSc, Department of Pediatric Oncology, Institute of Oncology, Hacettepe University, Ankara, 06100, Turkey (e-mail:

Received for publication March 30, 2009; accepted October 21, 2009

© 2010 Lippincott Williams & Wilkins, Inc.