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Pancreatoblastoma: Two Case Reports From a Medical Center in Taiwan

Huang, Yi-Ling MD*; Yang, Yung-Li MD*; Hsu, Wen-Ming MD, PhD; Lai, Hong-Shiee MD, PhD; Lin, Kai-Hsin MD*; Jou, Shiann-Tarng MD, PhD*; Lu, Meng-Yao MD*; Chang, Hsiu-Hao MD*; Lin, Dong-Tsamn MD*

Journal of Pediatric Hematology/Oncology: April 2010 - Volume 32 - Issue 3 - p 243-245
doi: 10.1097/MPH.0b013e3181bfd3ef
Clinical and Laboratory Observations
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Although pancreatoblastoma (PB) is an extremely rare tumor, it is the most common pancreatic tumor in children. We reported 2 cases of PB treated at a medical center in Taiwan. One was a 3.5-year-old boy who presented with abdominal pain. Physical examination demonstrated abdominal masses. Multiple pancreatic and hepatic masses were noted by magnetic resonance imaging. He underwent surgical resection but tumor could not be removed completely, which was confirmed by the pathology. He received chemotherapy consisting of cisplatin and doxorubicin after the surgery but the tumor progressed rapidly. He died of progressive disease and sepsis. The other case was a 4-year-old boy presented with abdominal pain. Computed tomography showed pancreatic tumor. He underwent surgical resection and pathology showed PB. He received chemotherapy after complete tumor resection. He is disease free till now. Complete tumor resection is the major difference of these 2 patients and is the most important factor affecting the outcome.

Departments of *Pediatrics

Surgery, National Taiwan University Hospital, Taipei, Taiwan

Reprints: Dong-Tsamn Lin, MD, Department of Laboratory Medicine and Pediatrics, College of Medicine, National Taiwan University, No. 7 Chung-San S. Road, Sec 1, Taipei 100, Taiwan (e-mail: dtlin@ntuh.gpv.tw).

Received for publication March 24, 2009

accepted September 4, 2009

© 2010 Lippincott Williams & Wilkins, Inc.