Original ArticlesTreatment of Cerebellopontine Angle Tumors in Children: A Single Institution's ExperienceTsai, Ming Horng MD*; Wong, Alex Mun-Ching MD†; Jaing, Tang-Her MD*; Wang, Huei-Shyong MD‡; Hsueh, Chuen MD§; Wu, Chieh-Tsai MD∥Author Information Divisions of *Hematology and Oncology ‡Neurology, Department of Pediatrics, Chang Gung Children's Hospital Departments of †Diagnostic Radiology §Pathology ∥Division of Neurosurgery, Department of Surgery, Chang Gung Memorial Hospital, Chang Gung University, Taoyuan, Taiwan Reprints: Tang-Her Jaing, MD, Division of Hematology and Oncology, Department of Pediatrics, Chang Gung Children's Hospital, Chang Gung University, 5 Fu-Shin Street, Kwei-Shan 333, Taoyuan, Taiwan (e-mail: firstname.lastname@example.org). Received for publication January 6, 2009 accepted April 10, 2009 Journal of Pediatric Hematology/Oncology: November 2009 - Volume 31 - Issue 11 - p 832-834 doi: 10.1097/MPH.0b013e3181acd842 Buy Metrics Abstract The authors discuss the current management for cerebellopontine angle (CPA) tumors in children. CPA tumors accounted for 1% to 3% of intracranial tumors in children. There had been much controversy with the management of these tumors. A total of 29 eligible patients were enrolled to the study and 5 patients had multiple lesions at diagnosis. Eight patients with tumors exclusively confined in the CPA. Sixteen patients with tumors occurred predominantly within CPA and 5 arising from the vicinity and growing mainly into the CPA. Twelve tumors were located in the right CPA (41%) and 5 (17%) on the left. Thirteen of the 29 patients developed hydrocephalus and 3 required placement of a shunt. Lesions of the CPAs were divided into those native to the angle and those extending to the angle from adjacent structures. Gross total removal was achieved in 9 cases, subtotal in 14, and 2 had biopsies only. Four patients were diagnosed with pontine glioma solely by magnetic resonance imaging without histologic confirmation. Two died soon after the operation. Ten patients died with a mortality rate of 34.5%. The median follow-up in this study was 38 months (range: 4 to 225 mo). The CPA is a rare location for lesions in children, with clear predominance on the right side. Although low-grade lesions are more frequent, the histology varies widely and is limited by the lack of radiologic-pathologic correlation. © 2009 Lippincott Williams & Wilkins, Inc.