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Disseminated Kikuchi-Fujimoto Disease Mimicking Malignant Lymphoma on Positron Emission Tomography in a Child

Lee, Dae Hyoung MD*; Lee, Jee Hyun MD*; Shim, Eun Jung MD*; Cho, Do Jun MD*; Min, Ki Sik MD*; Yoo, Ki Yang MD*; Min, Kwangseon MD

Journal of Pediatric Hematology/Oncology: September 2009 - Volume 31 - Issue 9 - p 687-689
doi: 10.1097/MPH.0b013e31819a5d77
Clinical and Laboratory Observations

Kikuchi-Fujimoto disease is a rare and benign disease, characterized by regional cervical lymphadenopathy with fever of unknown origin, affecting mainly young women. This self-limiting disease of unknown etiology has rarely been reported in children, so it has been frequently confused with malignancies. We describe a case of a child who was initially mistaken for malignant lymphoma because of multiple lymph nodes with 18-fluorodeoxyglucose uptake on positron emission tomography and was finally diagnosed with Kikuchi-Fujimoto disease by excisional biopsy of the affected lymph node.

Departments of *Pediatrics, Pyungchon-dong, Dongan-gu

Pathology, Sacred Heart Hospital, Hallym University, Anyang-si, Gyeonggi-do, Republic of Korea

Reprints: Dae Hyoung Lee, MD, Department of Pediatrics, Sacred Heart Hospital, Hallym University, Pyungchon-dong, Dongan-gu, Anyang-si, Gyeonggi-do, Republic of Korea (e-mail:

Received for publication October 22, 2008; accepted December 22, 2008

© 2009 Lippincott Williams & Wilkins, Inc.