Burkitt lymphoma (BL) is a rapidly dividing tumor that commonly presents itself in the jaw in its endemic form and the abdomen in the sporadic type. Central nervous system involvement at diagnosis is not uncommon, but there have been no previously published reports of BL involving the clivus. Increased tumor burden is associated with complications such as tumor lysis syndrome, and recognition of unusual presentations is important for timely management. We report 3 patients with BL involving the clivus at diagnosis.
Departments of *Pediatrics
†Division of Oncology
‡Department of Pathology and Laboratory Medicine, The Children's Hospital of Philadelphia, Philadelphia, PA
§Pathology and Laboratory Medicine, The University of Pennsylvania School of Medicine
No sources of financial support were used for this work.
Reprints: Dr Leslie S. Kersun, MD, Division of Oncology, Children's Hospital of Philadelphia, 34th and Civic Center Boulevard, Philadelphia, PA 19104 (e-mail: email@example.com).
Received for publication January 18, 2007; accepted November 12, 2007