Complementary and Alternative MedicineEvidence for Symptom Management in the Child With CancerLadas, Elena J. MS, RD*; Post-White, Janice RN, PhD, FAAN†; Hawks, Ria RN, MS, PNP‡; Taromina, Kathy MS, LAc* Author Information *Division of Pediatric Oncology, Integrative Therapies Program for Children with Cancer, Columbia University, 161 Ft. Washington, New York, NY 10032 †University of Minnesota, University of Minnesota School of Nursing, 707 Kenwood Parkway, Minneapolis, MN 55403 ‡Division of Bone Marrow Transplantation, Columbia University, 161 Ft. Washington, New York, NY 10032 Sources of Support/Acknowledgment: The Lerner and Schwartz Family, Origins Natural Resources. Reprints: Elena J. Ladas, MS, RD, Division of Pediatric Oncology, Integrative Therapies Program for Children with Cancer, Columbia University, 161 Ft. Washington, New York, NY 10032 (e-mail: [email protected]) Received for publication July 26, 2006; accepted August 1, 2006 Journal of Pediatric Hematology/Oncology: September 2006 - Volume 28 - Issue 9 - p 601-615 doi: 10.1097/01.mph.0000212989.26317.52 Buy Metrics Abstract The use of complementary/alternative medicine (CAM) has been well documented among children with cancer. This report summarizes the research evidence on the role of CAM therapies for prevention and treatment of the most commonly reported cancer-related symptoms and late effects among children with cancer. Small clinical trials document evidence of effectiveness for select therapies, such as acupuncture or ginger for nausea and vomiting, TRAUMEEL S for mucositis, and hypnosis and imagery for pain and anxiety. Several relatively small clinical trials of varying quality have been conducted on these CAM therapies in children with cancer. Some herbs have demonstrated efficacy in adults, but few studies of herbs have been conducted in children. Larger randomized clinical trials are warranted for each of these promising therapies. Until the evidence is more conclusive, the providers' role is to assess and document the child's use of CAM, critically evaluate the evidence or lack of evidence, balance the potential risks with possible benefits, and assist the family in their choices and decisions regarding use of CAM for their child with cancer. © 2006 Lippincott Williams & Wilkins, Inc.