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Lymphomatous Involvement of the Heart in Children: Two Cases and a Review of the Literature

Das, Prabodh K. MD*‡; Grant, Ronald MD*‡; Malkin, David MD*‡; Lee, Kyong-Jin MD†‡; Ngan, Bo MD§; MacDonald, Cathy E. MD; Carcao, Manuel MD*‡

Journal of Pediatric Hematology/Oncology: December 2004 - Volume 26 - Issue 12 - p 852-854
Clinical and Laboratory Observations
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Primary cardiac lymphoma (PCL) is a rare presentation of lymphoma in children. The emergency nature of its presentation (heart failure and arrhythmias) makes management of this entity difficult. The authors describe two children with lymphoma primarily involving the heart; one patient was a case of PCL and the other was a case of lymphoma involving the heart along with pelvic involvement. These two patients, together with a literature review on the topic, suggest that if the diagnosis of PCL is made early and treatment is expeditiously started, patients may do well.

From the *Division of Haematology/Oncology, The Hospital for Sick Children, Toronto, Canada; †Division of Cardiology, The Hospital for Sick Children, Toronto, Canada; ‡Department of Paediatrics, University of Toronto, Toronto, Canada; §Department of Laboratory Medicine, The Hospital for Sick Children, University of Toronto, Toronto, Canada; and ¶Department of Diagnostic Imaging, The Hospital for Sick Children, University of Toronto, Toronto, Canada.

Received for publication May 28, 2004; accepted September 27, 2004.

Reprints: Manuel Carcao, MD, FRCP(C), Division of Haematology/Oncology, The Hospital for Sick Children, 555 University Ave., Toronto, Ontario, Canada, M5G 1X8 (e-mail: manuel.carcao@sickkids.ca).

© 2004 Lippincott Williams & Wilkins, Inc.