Clinical and Laboratory ObservationsBullous Herpes Zoster in a Child With Leukemia: Case Report and Review of the LiteratureHaimi, Motti MD; Ben-Arush, Myriam Weyl MD; Kassis, Imad MD; Postovsky, Sergey MD; Kra-Oz, Zipi PhD; Elhasid, Ronit MDAuthor Information From the *Department of Pediatric Hemato-Oncology, Meyer Children’s Hospital, Rambam Medical Center, Haifa, Israel; †Infectious Diseases Unit, Meyer Children’s Hospital, Rambam Medical Center, Haifa, Israel; and ‡Virology Laboratory, Rambam Medical Center, Haifa, Israel. Received for publication April 17, 2004; accepted July 8, 2004. Reprints: Dr. Motti Haimi, Department of Pediatric Hemato-Oncology, Meyer Children’s Hospital, Rambam Medical Center, POB 9602, Haifa 31096, Israel (e-mail: email@example.com). Journal of Pediatric Hematology/Oncology: September 2004 - Volume 26 - Issue 9 - p 587-590 doi: 10.1097/01.mph.0000139451.37585.01 Buy Metrics Abstract Blistering disorders in childhood are usually difficult to diagnose and pose complicated management dilemmas. The incidence of herpes zoster in children with malignancy and immunodeficiency is greatly increased compared to normal children of comparable age. Although herpes zoster is known to occur in children with malignancy, the bullous form of herpes zoster is rare; to the authors’ knowledge, there was no previous report of this phenomenon in children in general and in children with cancer in particular. The authors describe a 3.5-year-old girl who was diagnosed with acute lymphoblastic leukemia; 7 months after presentation, during chemotherapy treatment, she developed the bullous form of herpes zoster on her right hand. The authors describe the method of diagnosis and provide a review of the literature concerning this rare phenomenon. Recognizing this entity and differentiating it from other bullomatous conditions enable the application of appropriate treatment, without unnecessary delay. Copyright © 2004 Wolters Kluwer Health, Inc. All rights reserved.