Article: PDF OnlyRíos Ernesto M.D.; Heresi, Gloria M.D.; Arevalo, Marianela M.T.American Journal of Pediatric Hematology/Oncology: October 1991 - p 296-299 Buy Abstract Three siblings with alloimmune neonatal neutropenia are presented. An immunoglobulin G (IgG) antineutrophil antibody specific for NA-2 antigen was demonstrated in maternal serum and in both of the three affected infants who were studied as neonates. The mother's neutrophils were negative for NA-2 antigen. The father and all four children, including the three known to be affected, had neutrophils that expressed NA-2 antigen. One patient studied sequentially demonstrated an inverse relationship between the antineutrophil antibody liter and the absolute neutrophil count. Exchange transfusions did not appear to benefit two of the infants. © Lippincott-Raven Publishers.