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Patrick Celeste H. M.D.; Lazarchick, John M.D.; Stubbs, Thomas M.D.; Pittard, William B. M.D.
American Journal of Pediatric Hematology/Oncology: July 1987
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Normal values for mean platelet volume (MPV) and platelet distribution width (PDW) have not been firmly established for term and preterm neonates. Cord blood samples from 143 healthy newborns (78 full term and 65 premature) were analyzed with the Coulter counter. Platelet count and MPV were significantly greater (p < 0.05 and p < 0.001, respectively) in term versus preterm infants, while PDW was significantly less in term infants (p < 0.001). Platelet count and MPV correlated with gestational age, and platelet count also correlated with birth weight. There was a significant (p < 0.001) negative correlation of PDW with gestational age and birth weight. These data represent normal reference ranges for neonates and demonstrate significant variation with gestational age.

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