Departments of ^aGenetics

^bBioengineering, School of Medicine, Stanford University, Stanford, California

^cDivision of Pharmaceutics, College of Pharmacy and Comprehensive Cancer Center, The Ohio State University, Columbus, Ohio, USA

Correspondence to Teri E. Klein, PhD, Shriram Center for Bioengineering and Chemical Engineering, 443 Via Ortega, Room 213, MC: 4245 Stanford, CA 94305, USA Tel: +1 650 725 0659; fax: +1 650 725 3863; e-mail: [email protected]

Received October 11, 2016

Accepted January 13, 2017