Departments of ^aGenetics

^bBioengineering, Stanford University, Stanford

^cKeck School of Medicine of University of Southern California, Los Angeles, California, USA

^dDepartment of Molecular Biology and Genetics, Democritus University of Thrace, Alexandroupolis, Greece

^eDepartment of Pharmacology, University of Oxford, Oxford, UK

Correspondence to Teri E. Klein, PhD, Department of Genetics, Stanford School of Medicine, Shriram Center, 443 Via Ortega, Room 213, Stanford, CA 94305-4125, USA Tel: +1 650 736 0156; fax: +1 650 725 3863; e-mail: [email protected]

Received March 23, 2016

Accepted May 5, 2016