^aDepartment of Experimental and Clinical Pharmacology

^bPUMA Institute of Personalized Medicine, University of Minnesota, Minneapolis, Minnesota

^cDepartment of Pharmaceutical Sciences, University of Colorado, Aurora, Colorado

Departments of ^dGenetics

^eBioengineering, Stanford University, Stanford, California, USA

Correspondence to Teri E. Klein, PhD, Department of Genetics, Stanford University Medical Center, 300 Pasteur Dr. Lane L301, Mail Code 5120, Stanford, 94305-5120 California, USA Tel: +1 650 725 0659; fax: +1 650 725 3863; e-mail: [email protected]

Received June 5, 2012

Accepted July 23, 2012