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Iv Commonwealth Congress On Diarrhoea And Malnutrition; Karachi, Pakistan; Meeting Of The Commonwealth Association Of Pediatric Gastroenterology And Nutrition; November 21-24, 1997

HELICOBACTER PYLORI: SIGNIFICANCE IN THE DEVELOPING WORLD

Weaver, Lawrence

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Journal of Pediatric Gastroenterology & Nutrition: August 1998 - Volume 27 - Issue 2 - p 243
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Abstract P5

Helicobacter pylori is probably the commonest bacterial infection of mankind. Gastric colonization with the microorganism is commoner in populations of the developing than developed world. Acquisition of infection occurs first in childhood, probably by a faeco-oral route. In adults H. pylori is the principal cause of duodenal ulcer disease, and there is epidemiological evidence of an association with gastric cancer. In children H. pylori infection is associated with diarrhoeal disease, undernutrition and growth impairment. Eradication of infection leads to healing of duodenal ulcers, but treatment is not presently recommended in asymptomatic carriers of the infection. The potential importance of H.pylori infection in developing countries is in its possible contribution to the aetiology of childhood malnutrition and to the genesis of gastric cancer.

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P = Plenary

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