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Prevalence and Risk Factors for Hypovitaminosis D in Young Patients With Inflammatory Bowel Disease

Pappa, Helen M.*; Langereis, Eveline J.; Grand, Richard J.*; Gordon, Catherine M.

Journal of Pediatric Gastroenterology and Nutrition: October 2011 - Volume 53 - Issue 4 - p 361–364
doi: 10.1097/MPG.0b013e3182250b3e
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ABSTRACT Vitamin D plays an important role in bone homeostasis. We aimed to report the prevalence of hypovitaminosis D in children with inflammatory bowel disease (IBD) and risk factors associated with low serum 25-hydroxyvitamin D (25OHD) concentration in children with IBD.

Risk factors for deficiency of this vitamin are similar to those in healthy children, with the addition of higher erythrocyte sedimentation rate. Both patients with ulcerative colitis and Crohn disease are at risk for hypovitaminosis D.

*Center for Inflammatory Bowel Disease, Children's Hospital Boston, Boston, MA

University of Amsterdam School of Medicine, Amsterdam, The Netherlands

Bone Health Program, Children's Hospital Boston, Boston, MA.

Address correspondence and reprint requests to Dr Helen M. Pappa, Division of Gastroenerology and Nutrition, Children's Hospital Boston, Hunnewell Ground, 300 Longwood Ave, Boston, MA 02115 (e-mail:

Received 22 November, 2010

Accepted 18 May, 2011

The authors report no conflicts of interest.

Copyright 2011 by ESPGHAN and NASPGHAN