Medical Progress: PDF OnlyKerner John A.; Stevenson, David K.; Hattner, Jo Ann; Cohen, Ronald S.; Schwartz, Herbert C.; Sunshine, PhilipJournal of Pediatric Gastroenterology and Nutrition: 1982 - p 59-62 Free Abstract Summary Forty-eight infants, including 14 premature infants who were appropriate size for gestational age (AGA), 10 full-term AGA infants, 18 full-term infants who were large for gestational age (LGA), and six premature LGA infants of diabetic mothers (IDMs). had measurements of skinfold thickness (SFT) in the first 72 h of life. For the 24 LGA infants, there was a significant positive correlation between maternal glycohemoglobin (Hb AIc.) in the postpartum period and SFT (r = 0.42, p < 0.05). Our observations in this study support those of others, demonstrating that SFT increases with increasing gestational age. In addition, they support the hypothesis that, in diabetic pregnancies, or pregnancies associated with an elevated Hb AIc, a reflection of the time-integrated blood glucose level over the weeks preceding parturition, fetal hyperglycemia and hyperinsulinemia stimulate increased triglyceride synthesis in adipose cells and lead to an increase in fetal subcutaneous fat. © Lippincott-Raven Publishers.