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Poster 46: Validation of a Quantitative Questionnaire for Stress and Urge Urinary Incontinence

Bent, A E.*; Gousse, A E.; Hendrix, S L.; Klutke, C G.§; Monga, A K.; Yuen, C K.; Muram, D**; Yalcin, I**

Journal of Pelvic Medicine and Surgery: 2005 - Volume 11 - Issue - p S46-S47
doi: 10.1097/01.spv.0000178924.99311.70
Poster Presentations: AUGS Abstracts: 2005 26th Annual Scientific Meeting of The American Urogynecologic Society

*Greater Baltimore Medical Center, Baltimore, MD; †University of Miami, Miami, FL; ‡Wayne State University, Detroit, MI; §Washington University School of Medicine, St. Louis, MO; ¶Princess Anne Hospital, Southampton, U.K.; ∥University of Manitoba, Winnipeg, Canada; and **Lilly Research Laboratories, Indianapolis, IN

Disclosure – Consultant: Eli Lilly: A.K. Monga, A.E. Bent, A.E. Gousse, S.L. Hendrix, C.G. Klutke, C.K. Yuen; Shareholder: Eli Lilly: I. Yalcin, R.C. Bump

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Primary care physicians often do not screen women for urinary incontinence (UI) or assess the relative importance of the major UI subtypes of stress UI (SUI) and urge UI (UUI). In an attempt to facilitate the screening process, we developed a 2-question quantitative questionnaire and validated its reproducibility and construct validity in a large clinical trial conducted in Canada, the United Kingdom, and the United States.

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The Stress/Urge Incontinence Questionnaire (S/UIQ) asks a patient to recall the number of SUI and UUI episodes she experienced over the preceding week. SUI and UUI episodes are described in lay terms using 2 questions: 1) “How many times in the last 7 days have you had an accidental leakage of urine onto your clothing, underwear, or pad during an activity such as coughing, sneezing, laughing, running, exercising, or lifting?” 2) “How many times in the last 7 days have you had an accidental leakage of urine onto your clothing, underwear, or pad with such a sudden strong need to urinate (Canada and United States)/pass water (United Kingdom) that you could not reach the toilet in time?” We evaluated the test–retest reproducibility (after 3 days) and the construct validity in 723 women, aged 19 to 85 years, enrolled in a randomized clinical trial. S/UIQ responses were used to classify symptoms as pure SUI, stress-predominant mixed UI (MUI), balanced MUI, urge-predominant MUI, and pure UUI. Correlating S/UIQ responses with other measures of incontinence severity, bother, and impact established construct validity.

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Reproducibility for the classification of symptoms was moderately strong (kappa = 0.536). Test–retest agreement was good (64–86%) for all but balanced MUI (38%). Intraclass correlations revealed good reproducibility for the number of incontinence episodes (0.726 for all IE, 0.694 for stress IE, and 0.703 for urge IE). Construct validity was established by demonstrating significant (all P<0.01) Spearman Rho values for IE from a lockout electronic diary (0.82), the International Consultation on Incontinence Questionnaire Short Form (ICIQ-SF) score (0.63), the Incontinence Quality of Life (I-QOL) questionnaire score (−0.38), and 2 global severity and bother scales (0.40 and 0.25).

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The data show that the S/UIQ is a reproducible quantitative questionnaire with good construct validity for UI and suggest the S/UIQ could be useful in primary care settings to allow providers to characterize and quantify symptoms before and during treatment.

© 2005 Lippincott Williams & Wilkins, Inc.