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Comparison of Urodynamic Findings in Women With Anatomical Versus Functional Bladder Outlet Obstruction

Brucker, Benjamin M. MD; Shah, Sagar MD; Mitchell, Sarah MD; Fong, Eva MD; Nitti, Matthew D. BA; Kelly, Christopher E. MD; Rosenblum, Nirit MD; Nitti, Victor W. MD

Female Pelvic Medicine & Reconstructive Surgery: January/February 2013 - Volume 19 - Issue 1 - p 46–50
doi: 10.1097/SPV.0b013e31827d87cc
Original Article

Objectives To characterize the symptoms and urodynamic findings of anatomical bladder outlet obstruction (AO) and functional bladder outlet obstruction (FO) in women and to determine if future endeavors at defining bladder outlet obstruction in women can group these entities together.

Methods Retrospective review of all videourodynamic studies was performed on women from March 2003 to July 2009. Women with diagnosis of obstruction were categorized based on the cause of obstruction into 2 groups: AO and FO. Demographic data, symptoms, and urodynamic findings were compared between the 2 groups.

Results One hundred fifty-seven women were identified of which 86 (54.8%) were classified as having AO and 71 (45.2%) were classified as having FO. There were no differences in symptoms between the 2 groups. There was no difference (P=0.5789) in the mean detrusor pressure at maximum flow rate Q max between AO (38.9 cm H20) and FO (41.0 cm H20). There was a difference in the Q max between AO and FO (10.6 [0–41.7] and 7.4 [0–35.7] mL/s, respectively; P=0.0044), but there was considerable overlap between the values in these 2 groups.

Conclusions Anatomical bladder outlet obstruction and FO have similar urodynamic voiding pressure findings, but Q max was statistically significantly lower in AO. However, there is a large overlap in the Q max values between the 2 groups. Therefore, future studies that attempt to characterize bladder outlet obstruction in women need not exclude either group.

Anatomical bladder outlet obstruction and functional bladder outlet obstruction in women have similar urodynamic voiding pressure findings.

From the Department of Urology, New York University Langone Medical Center, New York, NY.

Reprints: Benjamin M. Brucker, MD, 150 E 32nd St, Second Floor, NY, NY 10016. E-mail:

Dr Benjamin Brucker is a consultant for Ferring. Dr Victor Nitti is a consultant for Alleran, Astellas, AMS, Medtronic, Pfizer, Serenity, Uroplasty; Investigator for Astellas, Allergan, AMS, Coloplast. Lectures for Allergan, Stock holder for Serenity.

The other authors declare that they have nothing to disclose.

© 2013 by Wolters Kluwer Health | Lippincott Williams & Wilkins