To examine the prevalence of lower urinary tract symptoms (LUTS) in women with symptomatic uterine fibroids and investigate their relationship with fibroid location and uterine volume.
This was a cross-sectional study including 78 women seeking surgical treatment for symptomatic uterine fibroids. The validated Bristol Female Lower Urinary Tract Symptom-Scored Form (BFLUTS-SF) questionnaire was administered before surgical intervention. Uterine volume and BFLUTS-SF subscale scores or symptoms were compared using Student t test. Multivariate models explored the association between dominant fibroid location and BFLUTS-SF subscale scores.
The most prevalent LUTS were nocturia (91%), urgency (59%), and urinary incontinence (45%-54%). Mean uterine volume and length were 672 ± 714 cm3 and 13 ± 4.24 cm, respectively. Women with moderate and severe urinary urgency had significantly larger uterine volumes (P = 0.017). Mean voiding subscale scores were significantly higher in women with dominant anterior fibroids compared with those with non-anterior fibroids (voiding subscale scores, 2.84 ± 3.03 vs 1.30 ± 2.07, respectively; P < 0.01). This remained significant after adjusting for age, parity, body mass index, and imaging modality.
Lower urinary tract symptoms are prevalent in patients with symptomatic uterine fibroids. Further study is needed to determine if surgical therapy improves these LUTSs in this population.
Description: Urinary urgency and voiding dysfunction are significantly associated with large fibroid uteri and anterior fibroid location.
From the *Division of Women's Pelvic Medicine and Reconstructive Surgery,Department of Obstetrics and Gynecology, University of Alabama at Birmingham, Birmingham, AL; †Chestnut Hill Women's Health Associates; and ‡Division of Urogynecology and Reconstructive Pelvic Surgery, Department of Obstetrics and Gynecology, University of Pennsylvania School ofMedicine, Philadelphia, PA.
Reprints: Gina Northington, MD, PhD, Division of Urogynecology and Reconstructive Pelvic Surgery, Department of Obstetrics and Gynecology, The Hospital of the University of Pennsylvania, 3400 Spruce St./1000 Ravdin Courtyard, Philadelphia, PA 19104. E-mail: firstname.lastname@example.org.