Catalyzing Novel Approaches to Rapid, Accurate, and Affordable Early Cancer DetectionDhar, Asif, MD; Meagher, Beth, MA; Ryscavage, Andrew, MA, MBAThe Cancer Journal: May/June 2018 - Volume 24 - Issue 3 - p 115–120 doi: 10.1097/PPO.0000000000000314 Review Articles Buy SDC Abstract Author InformationAuthors Article MetricsMetrics Inspired by the Cancer Moonshot, a dedicated team of professionals worked with leaders across the cancer ecosystem to look for an opportunity to radically reduce cancer mortality globally by focusing on early cancer detection. After an initial survey of cancer innovation, progress, and pitfalls, the team believed that if new rapid, affordable, and accurate early detection solutions were appropriately brought to market, it would be possible to intervene earlier when cancer is most treatable. An extensive process began, informed by dozens of experts in the cancer ecosystem. The Cancer XPRIZE team designed a prize competition where “the winning team will develop a means to rapidly, accurately, and affordably screen for early cancers where intervention can reduce human suffering.” The following outlines the Cancer XPRIZE's experience using a powerful approach—the radical prize design—to catch more cancers in time to make a difference saving lives, dollars, and suffering. From Deloitte Consulting, LLP, Arlington, VA. The authors have disclosed that they have no significant relationships with, or financial interest in, any commercial companies pertaining to this article. Reprints: Andrew Ryscavage, MA, MBA, Deloitte Consulting, LLP, 1919 N Lynn St, Arlington, VA 22209. E-mail: firstname.lastname@example.org. Copyright © 2018 Wolters Kluwer Health, Inc. All rights reserved.