Secondary Logo

Journal Logo

Institutional members access full text with Ovid®

Charged Particle Therapy: The Physics of Interaction

Lomax, Antony J. PhD

doi: 10.1097/PPO.0b013e3181af5cc7
Special Issue on Charged Particle Therapy: Review Article

Particle therapy has a long and distinguished history with more than 50,000 patients having been treated, mainly with high-energy proton therapy. Particularly, for proton therapy, there is an increasing interest in exploiting the physical characteristics of charged particles for further improving the potential of radiation therapy. In this article, we review the most important interactions of charged particles with matter and describe the basic physical principles that underlie why particle beams behave the way they do and why such a behavior could bring many benefits in radiation therapy.

From the Centre for Proton Radiotherapy, Paul Scherrer Institute, Switzerland.

Reprints: Antony J. Lomax, PhD, Centre for Proton Radiotherapy, Paul Scherrer Institute, 5232 Villigen-PSI, Switzerland. E-mail:

© 2009 Lippincott Williams & Wilkins, Inc.