Original ArticleThe Effects of Safety Climate on Psychosocial Factors: An Empirical Study in Healthcare WorkplacesWang, Jiana-Fu PhD∗; Wu, Chieh-Liang PhD†; Tsai, Yao-Te PhD‡; Weng, Shao-Jen PhD§; Hsu, Ya-Chen PhD∥ Author Information From the ∗Department of Marketing, National Chung Hsing University †Department of Critical Care Medicine, Taichung Veterans General Hospital ‡ Department of International Business, Feng Chia University Departments of §Industrial Engineering and Enterprise Information ∥ Food Science, Tunghai University, Taichung City, Taiwan. Correspondence: Yao-Te Tsai, PhD, Department of International Business, Feng Chia University, No. 100, Wenhua Rd, Taichung City 407, Taiwan. E-mail: [email protected]; and Shao-Jen Weng, PhD, Department of Industrial Engineering and Enterprise Information, Tunghai University, No. 1727, Section 4, Taiwan Boulevard, Taichung City 407, Taiwan. E-mail: [email protected] The authors disclose no conflict of interest. J.-F.W. and C.-L.W. contributed equally to this work. Data are available upon request from the authors. Journal of Patient Safety 18(2):p e528-e533, March 2022. | DOI: 10.1097/PTS.0000000000000856 Buy Metrics Abstract How to develop a better patient safety culture has been an important goal for healthcare organizations, but the effects of safety culture on psychosocial factors, such as emotional exhaustion and stress, have not been fully addressed. This study aimed to reconfigure important dimensions affecting safety culture and examine the associations between safety culture and psychosocial factors (emotional exhaustion and work-life balance). The partial least squaring technique was used to analyze the data, showing that job satisfaction (β = 0.320, P < 0.001), working conditions (β = 0.307, P < 0.001), and perception of management (β = 0.282, P < 0.001) positively affected the safety climate. The safety climate and work-life balance could reduce the occurrence of emotional exhaustion, whereas a high-stress environment would cause a higher level of emotional exhaustion. Given these findings, hospitals should endeavor to help employees feel safe and not threatened, reduce stress, and advise them to maintain a good work-life balance. Copyright © 2021 Wolters Kluwer Health, Inc. All rights reserved.