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A Comparative Study of Blood Sampling From Venipuncture and Short Peripheral Catheters in Pediatric Inpatients

Twibell, K. Renee PhD, RN, CNE; Hofstetter, Paula BSN, RN; Siela, Debra PhD, RN, CCNS, ACNS-BC, CCRN-K, CNE, RRT; Brown, Dava BSN, RN, CRNI®, VA-BC; Jones, Holly M. MSN, RNC-OB, RN-BC

doi: 10.1097/NAN.0000000000000338

This prospective, comparative study examined blood test results, hemolysis rates, and patient perceptions related to 2 blood sampling methods in pediatric inpatients (N = 95). Blood specimens were drawn via venipuncture and a short peripheral catheter used for fluid administration. Results revealed no significant differences in potassium and glucose levels. No clinically significant difference in hemoglobin was noted. Hemolysis rates were 4% for venipuncture samples and 15% when drawn from peripheral catheters. One catheter became occluded after a blood draw. Patients/parents rated distress and dissatisfaction with venipuncture as significantly greater compared with short peripheral catheter blood sampling (P < .001).

Ball State University, Muncie, Indiana (Drs Twibell and Siela); Indiana University Health Ball Memorial Hospital, Muncie, Indiana (Dr Twibell and Mss Hofstetter, Brown, and Jones).

K. Renee Twibell, PhD, RN, CNE, is an associate professor in the School of Nursing at Ball State University and a nurse researcher at Indiana University (IU) Health Ball Memorial Hospital. Dr Twibell serves on state and national nursing committees. She has published more than 25 articles and presented more than 120 times at professional conferences. Paula Hofstetter, BSN, RN, has 20 years of experience in pediatrics and 10 years in obstetrics. She serves as a unit preceptor, co-chair of the Pediatric Unit Based Council, member of the hospital-wide Professional Nursing Council, and nursing representative on the Value Analysis Team at IU Health Ball Memorial Hospital. Ms Hofstetter was the primary research assistant for this study. Debra Siela, PhD, RN, CCNS, ACNS-BC, CCRN-K, CNE, RRT, is an associate professor at Ball State University School of Nursing. She has a PhD in nursing and is certified in several nursing specialties. In addition to her research expertise, Dr Siela has presented at national nursing conferences and has published numerous articles in nursing-related journals. Dava Brown, BSN, RN, CRNI®, VA-BC, was the team leader of the vascular access department at IU Health Ball Memorial Hospital for more than 10 years. She is certified in vascular access and infusion therapy. Ms Brown is a consultant, researcher, published author, and nurse leader. Holly M. Jones, MSN, RNC-OB, RN-BC, works as a nursing professional development educator at IU Health Ball Memorial Hospital. She earned an MSN in education and is certified in inpatient obstetrics and nursing professional development. Ms Jones also serves as a fetal monitor and obstetric patient safety instructor, as well as a chapter coordinator for a national nursing organization focused on the care of child-bearing families.

Corresponding Author: K. Renee Twibell, PhD, RN, CNE, School of Nursing, College of Health, Ball State University, 2000 W. University Ave., Muncie, IN 47306 (

Dava Brown, BSN, RN, CRNI®, VA-BC, received the Infusion Nurses Society Gardner Foundation Research Grant that contributed to the funding of this study. The other coauthors of this article have no conflicts of interest to disclose.

© Copyright 2019 by Infusion Nurses Society