The ambulatory infusion clinic model is a safe and cost-efficient alternative to home infusion. Programs are based in physician offices, hospital outpatient departments, freestanding clinics, and long-term care facilities. The ambulatory infusion nurse assists the physician with patient selection and development of a plan for treatment. The nurse is responsible for coordination of reimbursement authorization as well as patient enrollment and education. Intravenous immunoglobulin often is administered on site in the clinic, where the nurse initiates and maintains venous access, often compounds the drug, monitors the infusion, and assesses the patient's response.