As infusion therapies increasingly move from the hospital to the home setting, home I.V. therapy nurses must frequently decide which therapies are appropriate for home delivery. These practitioners must find innovative, cost-effective, and, most important, safe methods of providing new I. V. therapies in the home. A medically complex patient with a strong desire to maintain the most normal lifestyle possible was introduced to our infusion team. We accomplished our goal—to institute and maintain home therapy on this patient—by designing a treatment proposal that outlined specific guidelines, criteria, and recommendations for all aspects of the infusion care. This proposal can serve as a model for any experimental or unusual treatment being considered for home therapy.