State-of-the-ArtThe Effects of Diabetes and Diabetic Medications on Bone HealthElamir, Yasmine MD*; Gianakos, Arianna L. DO†; Lane, Joseph M. MD‡; Sharma, Anupa MD§; Grist, William P. MD*; Liporace, Frank A. MD†; Yoon, Richard S. MD†Author Information *Departments of Internal Medicine, and †Orthopedic Surgery, Jersey City Medical Center, RWJ Barnabas Health, Jersey City, NJ; ‡Department of Orthopedic Surgery, Hospital for Special Surgery, New York, NY; and §Department of Endocrinology, Robert Wood Johnson University Hospital, New Brunswick, NJ. Reprints: Richard S. Yoon, MD, Department of Orthopedic Surgery, Jersey City Medical Center, RWJ Barnabas Health, 355 Grand St, Jersey City, NJ 07302 (e-mail: [email protected]). The authors report no conflict of interest. Journal of Orthopaedic Trauma: March 2020 - Volume 34 - Issue 3 - p e102-e108 doi: 10.1097/BOT.0000000000001635 Buy Metrics Abstract Summary: The incidence and prevalence of diabetes continues to increase, and proper understanding of the adverse effects on bone metabolism is important. This review attempts to discuss the pathophysiology of the effects of diabetes and diabetic medications on bone metabolism and bone health. In addition, this review will address the mechanisms resulting in increased fracture risk and delayed bone healing to better treat and manage diabetic patients in the orthopedic clinical setting. Copyright © 2019 Wolters Kluwer Health, Inc. All rights reserved.