Low serum albumin levels (hypoalbuminemia
) have classically been used to identify malnutrition
. The effect of increasing severity of malnutrition
on postoperative outcomes in patients undergoing hip fracture
surgery has not been well delineated on a large scale.
A total of 12,373 patients undergoing hip fracture
surgery from 2006 to 2013 National Surgery Quality Improvement Project data were identified.
Patient demographic, comorbidity, and preoperative laboratory data and complication, reoperation, and readmission data were collected.
Main Outcome Measurements:
Multivariate logistic regression was used to determine the effect of increasing severity of malnutrition
on rates of 30-day postoperative complications, readmissions, and reoperations.
A total of 12,373 hip fractures met inclusion criteria. A total of 6506 (52.6%) patients had normal albumin levels (albumin ≥3.5 g/dL), 3205 (25.9%) patients were mildly malnourished (albumin 3.1–3.49 g/dL), 2265 (18.3%) were moderately malnourished (albumin 2.4–3.1 g/dL), and 397 (3.2%) patients were severely malnourished (albumin <2.4 g/dL). Mean age was similar between the 4 cohorts (P
< 0.001). Severe malnutrition
was associated with a 2-fold increase in the odds of postoperative complications and mortality when compared with mild malnutrition
< 0.001). Increasing severity of malnutrition
was associated with significantly longer lengths of stay and higher odds of experiencing a related readmission (P
Increasing severity of hypoalbuminemia
is independently associated with poorer outcomes in the 30 days after hip fracture
Level of Evidence:
Prognostic Level III. See Instructions for Authors for a complete description of levels of evidence.