Technical TricksBone Marrow Sampling in Pathologic Fractures: Intramedullary Pediatric Chest Tube TechniqueJohnson, Jeremy C. MD; Kneisl, Jeffrey S. MD Author Information From the Department of Orthopaedic Surgery and Blumenthal Cancer Center, Carolinas Medical Center, Charlotte, NC. The authors and institutions received no financial support directly or indirectly relating to this project. The legal/regulatory status of the device that is subject of this manuscript is not known by the authors. Note: No device is implanted permanently. Reprints: Jeffrey S. Kneisl, MD, Department of Orthopaedic Surgery, P.O. Box 32861, Charlotte, NC 28232-2861 (e-mail: [email protected]). Accepted for publication June 12, 2003. Journal of Orthopaedic Trauma 18(5):p 306-309, May 2004. Buy Abstract Summary: The objective of this article is to report upon a simple technique of bone marrow specimen collection of intramedullary bone tumors using a pediatric chest tube. This technique is described along with two case reports which include a 60-year-old female with metastatic breast cancer to the proximal femur, and a 63-year-old male with multiple myeloma of the proximal humerus. Utilizing this technique, in our experience, over 50 mL of aspirate can be obtained and definitive histologic material for cytogenetic diagnosis and immunohistochemistry. This technique is not indicated for biopsy of suspected primary lesions of bone due to the possibility of medullary or hematologic seeding and inappropriate invasion of soft tissue compartments. © 2004 Lippincott Williams & Wilkins, Inc.