Brief ReportDepression A Gut “Microbiome” Feeling!Naguy, Ahmed MBBch, MSc∗; Pridmore, Saxby MD†; Abuzeid, Mohamed Y. MD, PhD‡,§; Thiguti, Sri Haricharan MD, MRCPsych (UK)∥; Alamiri, Bibi MD, ABPN, ScD∗,¶Author Information ∗Al-Manara CAP Centre, Kuwait Centre for Mental Health, Shuwaikh, Kuwait †University of Tasmania, Hobart, Australia ‡Ain Shams Institute of Psychiatry, Ain Shams Faculty of Medicine, Cairo, Egypt §Kuwait Centre for Mental Health, Shuwaikh, Kuwait ∥Stoke-on-Trent, United Kingdom ¶Tufts University, Medford, Massachusetts. Send reprint requests to Ahmed Naguy, MBBch, MSc, Al-Manara CAP Centre, Kuwait Centre for Mental Health, Jamal Abdul-Nassir St, Shuwaikh, Sulibikhat 21315, Kuwait. E-mail: [email protected]. The Journal of Nervous and Mental Disease: September 2021 - Volume 209 - Issue 9 - p 691-692 doi: 10.1097/NMD.0000000000001365 Buy Metrics Abstract Burgeoning body of evidence from neuroscience is pouring in highlighting a potential association between gut microbiota with the pathophysiology of depression and anxiety. Manipulation of gut microbiota may be then useful to decode this role and to provide novel therapeutics for major depressive disorder (MDD), developing microbiota-related biomarkers to stratify patients at risk and to delineate more homogeneous biotypes of MDD. Copyright © 2021 Wolters Kluwer Health, Inc. All rights reserved.