Original ArticlesGeneralized Anxiety Disorder During the COVID-19 Outbreak in Iran The Role of Social DysfunctionZakeri, Mohammad Ali MSc∗; Hossini Rafsanjanipoor, Sayed Mortaza MSc†; Kahnooji, Mahmood MD‡; Ghaedi Heidari, Fatemeh PhD§; Dehghan, Mahlagha PhD∥ Author Information ∗Non-Communicable Diseases Research Center †Social Determinants of Health Research Centre ‡Department of Internal Medicine, Faculty of Medicine, Rafsanjan University of Medical Sciences, Rafsanjan §Department of Psychiatric Nursing, Nursing and Midwifery School, Isfahan University of Medical Sciences, Isfahan ∥Nursing Research Center, Kerman University of Medical Sciences, Kerman, Iran. Send reprint requests to Mahlagha Dehghan, PhD, Razi Faculty of Nursing and Midwifery, Kerman University of Medical Sciences, Haft-Bagh Highway, Kerman, 7616913555, Iran. E-mail: [email protected], [email protected]. Data are available by contacting with the corresponding author by e-mail. The Journal of Nervous and Mental Disease: July 2021 - Volume 209 - Issue 7 - p 491-496 doi: 10.1097/NMD.0000000000001320 Buy Metrics Abstract The COVID-19 epidemic has both physical and psychosocial consequences for the general population. The present study aimed to investigate the relationship between the prevalence of generalized anxiety disorder (GAD) and social dysfunction during the COVID-19 epidemic in Iran. This cross-sectional web-based study was conducted on 1000 Rafsanjani citizens in southeastern Iran. Data were collected by using the Generalized Anxiety Disorder-7 and the General Health Questionnaire from March 15 to March 30, 2020. The prevalence of GAD was 27.8%. The mean score of social functioning was 9.71 ± 2.66, and all participants had social dysfunction. Multivariate logistic regression test showed a significant correlation between anxiety and social functioning (confidence interval [CI], 1.16–1.30; p < 0.001), sex (CI, 1.49–3.04; p < 0.001), and concern about COVID-19 (CI, 1.38–2.73; p < 0.001). The COVID-19 epidemic had negative psychosocial consequences in the general population in Iran. Copyright © 2021 Wolters Kluwer Health, Inc. All rights reserved.