Original ArticlesOlfactory Function in Depressed AdolescentsUzun Cicek, Ayla MD∗; Altuntas, Emine Elif MD, PhD†; Bora, Adem MD†; Sarı, Seda Aybuke MD∗Author Information Departments of ∗Child and Adolescent Psychiatry †Otorhinolaryngology, Faculty of Medicine, Cumhuriyet University, Sivas, Turkey. Send reprint requests to Ayla Uzun Cicek, MD, Department of Child and Adolescent Psychiatry, Faculty of Medicine, Cumhuriyet University, Yenisehir, Kayseri St, No. 43, Sivas 58140, Turkey. E-mail: [email protected]. The Journal of Nervous and Mental Disease: June 2020 - Volume 208 - Issue 6 - p 476-480 doi: 10.1097/NMD.0000000000001148 Buy Metrics Abstract Some researchers have suggested that olfactory deficits might be a sensitive marker for depression in adults. However, olfactory function has not been well studied in relation to depression among children and adolescents. The aim of this study was to evaluate the effect of depression on olfactory function of adolescents. The olfactory threshold, odor identification, and discrimination abilities of adolescents aged 12 to 17 (43 adolescents with major depressive disorder and 43 healthy controls) alongside their sum were evaluated using the Sniffin’ Sticks extended test. Olfactory scores were similar between the groups. However, depressed adolescents perceived their own olfactory function scores significantly lower than the measured values. No correlation was found between olfactory scores and age, sex, severity of depression, and duration of depression. This study conducted with a small sample size revealed that olfactory function of the adolescents with depression was similar to olfactory function of the healthy adolescents. It is required to conduct further adequately powered, longitudinal studies in order to verify these results. Copyright © 2020 Wolters Kluwer Health, Inc. All rights reserved.