Original ArticlesSleep Quality and Health-Related Quality of Life in Older People With Subjective Cognitive Decline, Mild Cognitive Impairment, and Alzheimer DiseaseLeng, Minmin MD*; Yin, Huiru PhD*; Zhang, Ping PhD†; Jia, Yong PhD*; Hu, Mingyue MD*; Li, Guichen MD*; Wang, Chunyan PhD‡; Chen, Li PhD*Author Information *School of Nursing, Jilin University, Changchun †School of Nursing, Southern Medical University, Guangzhou ‡Senior Officials Inpatient Ward, First Hospital of Jilin University, Changchun, China. ML and HY contributed equally to this work. Send reprint requests to Li Chen, PhD, School of Nursing, Jilin University, 965 Xinjiang St, Changchun 130021, China. E-mail: firstname.lastname@example.org; Chunyan Wang, PhD, The First Hospital of Jilin University, 71 Xinmin St, Changchun 130021, China. E-mail: email@example.com. The Journal of Nervous and Mental Disease: May 2020 - Volume 208 - Issue 5 - p 387-396 doi: 10.1097/NMD.0000000000001137 Buy Metrics Abstract We aimed to investigate sleep quality and health-related quality of life (HRQOL) in older adults with subjective cognitive decline (SCD), mild cognitive impairment (MCI), and Alzheimer disease (AD). A total of 221 participants were divided into the following five groups: normal controls (NCs), SCD without memory concerns (SCD-0), SCD with memory concerns (SCD-1), MCI, and AD according to their cognitive status. Compared with NC, individuals with SCD-0, SCD-1, MCI, and AD had more sleep problems and reduced HRQOL. Participants with poor sleep quality had an increased risk of cognitive impairment compared with participants with good sleep quality. Within all five subgroups, individuals with poor sleep quality reported more difficulties in HRQOL than individuals with good sleep quality. Future studies employing a longitudinal design, larger samples, and objective evaluation tools are needed. Copyright © 2020 Wolters Kluwer Health, Inc. All rights reserved.