Review ArticlesRelaxation Therapy for Depression An Updated Meta-analysisJia, Yong PhD∗; Wang, Xiaowei BSc†; Cheng, Yuanjuan MD‡ Author Information ∗School of Nursing †School of Public Health ‡The Second Hospital, Jilin University, Changchun, China. Yong Jia and Xiaowei Wang are co-first authors. Send reprint requests to Yuanjuan Cheng, MD, The Second Hospital, Jilin University, No. 218 Ziqiang St, Changchun, Jilin 130021, China. E-mail: [email protected]. Supplemental digital content is available for this article. Direct URL citations appear in the printed text and are provided in the HTML and PDF versions of this article on the journal’s Web site (www.jonmd.com). The Journal of Nervous and Mental Disease: April 2020 - Volume 208 - Issue 4 - p 319-328 doi: 10.1097/NMD.0000000000001121 Buy SDC Metrics Abstract We conducted this updated meta-analysis to evaluate the effects of relaxation therapy for depression. We searched PubMed, MEDLINE, PsycINFO, the Cochrane Library, Web of Science, and CINAHL for randomized controlled trials evaluating the effects of relaxation therapy in patients with depression. Finally, 14 studies were included in this meta-analysis. The efficacy of the intervention was evaluated using depression scale scores. We found that there was no significant difference between the effects of relaxation therapy and psychotherapy on decreasing self-rated depressive symptoms (standardized mean difference [SMD] = 0.19; 95% confidence interval [CI], −0.11 to 0.48). In addition, eight trials compared relaxation therapy with no treatment, waiting list, or minimal treatment and showed that the relaxation group reported lower levels of self-reported depression scores postintervention (SMD = −0.57; 95% CI, −0.98 to −0.15). Therefore, this meta-analysis showed that relaxation might reduce depressive symptoms, and the effect is not worse than that of psychotherapy. Copyright © 2020 Wolters Kluwer Health, Inc. All rights reserved.