Original ArticlesVery Long-Term Outcome of Community-Dwelling Patients With Schizophrenia Spectrum Disorders in Rural GreecePeritogiannis, Vaios MD, MSc, PhD*; Grammeniati, Aikaterini MSc*; Gogou, Afroditi BSc*; Gioti, Panagiota BSc*; Mavreas, Venetsanos MD, PhD†Author Information *Mobile Mental Health Unit of the Prefectures of Ioannina-Thesprotia, Society for the Promotion of Mental Health in Epirus †University of Ioannina, Ioannina, Greece. Send reprint requests to Aikaterini Grammeniati, MSc, Thoma Pashidi 54, Ioannina, Greece, P.C. 45445. E-mail: firstname.lastname@example.org. Online date: November 8, 2019 The Journal of Nervous and Mental Disease: December 2019 - Volume 207 - Issue 12 - p 1012-1018 doi: 10.1097/NMD.0000000000001068 Buy Metrics Abstract The objective of the present study was to measure the very long-term outcome in community-dwelling patients with a diagnosis of psychosis and to search for possible correlations of outcome with clinical factors. The sample included 55 psychotic patients with at least 15 years of disease duration (M = 32.1 years). For the estimation of the outcome, the Health of the Nations Outcome Scale and the Clinical Global Impression Scale were used. A total of 34.5% of the patients had a good outcome, whereas 27.3% had poor outcome. Outcome was found to be correlated to symptoms, and it was significantly worse in patients living with other severely mentally ill family members. In our study, outcome was good in more than a third of patients. Both symptoms and social functioning were associated with outcome. This study may have some implications for mental healthcare delivery. Copyright © 2019 Wolters Kluwer Health, Inc. All rights reserved.