Original ArticlesAssociation of Suicide Attempt With Seroprevalence of Toxoplasma gondii in AdolescentsSari, Seda Aybuke MD*; Kara, Ahu MD†Author Information Departments of *Child and Adolescent Psychiatry †Pediatric Infectious Diseases, Sivas Cumhuriyet University School of Medicine, Sivas, Turkey. Send reprint requests to Seda Aybuke Sari, MD, Department of Child and Adolescent Psychiatry, Sivas Cumhuriyet University School of Medicine, 58140, Imaret Village, Central Sivas, Turkey. E-mail: email@example.com. Online date: November 1, 2019 The Journal of Nervous and Mental Disease: December 2019 - Volume 207 - Issue 12 - p 1025-1030 doi: 10.1097/NMD.0000000000001046 Buy Metrics Abstract In this study, we aimed to explore the potential pathophysiological relationship between suicide attempts and Toxoplasma gondii infection. Fifty patients aged between 12 and 18 years who attempted suicide and 50 healthy adolescents were included in this study. All adolescents were evaluated by a child psychiatrist using a semistructured interview and Rosenberg Self-Esteem Scale (RSES), Children's Depression Inventory (CDI), and Inventory of Parent and Peer Attachment. T. gondii IgM and IgG antibodies of patients and control subjects were analyzed from blood samples by enzyme-linked immunosorbent assay. Psychiatric disorders particularly mood disorders were more common in adolescents in the patient group. Adolescents attempting suicide were found to have worse relationships with their parents; their CDI scores were higher, and their RSES scores were lower than their healthy peers. There were no significant differences between the patient and the control groups in terms of Toxoplasma IgG antibody positivity. Although the seropositivity of Toxoplasma IgG antibody was higher in the patient group than that in the control group, the difference between the two groups was not statistically significant. Copyright © 2019 Wolters Kluwer Health, Inc. All rights reserved.