Original ArticlesUncovering Demographic, Clinical, Triggering Factors Similarities Between Migraine and Irritable Bowel Syndrome A Prospective StudyHajj, Aline PharmD, PhD∗,†; Mourad, Diane PharmD∗,†; Ghossoub, May MD‡; Hallit, Souheil PharmD, MSc, MPH, PhD§,∥; Geagea, Antoine MD¶; Abboud, Halim MD#; El Mouallem, Hanna PharmD†; Saniour, Philippe MD∗∗; El Hachem, Nabil DO††; Rabbaa Khabbaz, Lydia PharmD, PhD∗,†Author Information ∗Laboratory of Pharmacology, Clinical Pharmacy, and Quality Control of Drugs, Faculty of Pharmacy, Pôle Technologie-Santé, Saint-Joseph University †Faculty of Pharmacy, Saint-Joseph University ‡Department of Neurology, Levant Hospital, Beirut, Lebanon §Faculty of Medicine and Medical Sciences, Holy Spirit University of Kaslik (USEK), Jounieh, Lebanon ∥INSPECT-LB: Institut National de Santé Publique, Epidémiologie Clinique et Toxicologie ¶Department of Gastroenterology, Levant Hospital #Department of Neurology, Saint-Joseph University, Hôtel-Dieu de France Hospital ∗∗Department of Gastroenterology, Saint-Joseph Hospital, Beirut, Lebanon ††Department of Osteopathy, Fondation EFOM Boris Dolto, Paris, France. Aline Hajj and Diane Mourad contributed equally to this work. Send reprint requests to Aline Hajj, PharmD, PhD, Laboratoire de Pharmacologie, Pharmacie Clinique et Contrôle de Qualité des Médicaments, Faculté de Pharmacie, Université Saint-Joseph, Campus des Sciences Médicales et Infirmières, Rue de Damas, BP 11-5076 Riad El Solh, Beirut 1107-2180, Lebanon. E-mail: [email protected]. Authors contributions: Aline Hajj, Nabil El Hachem, Hanna El Mouallem, and May Ghossoub designed the research study; Aline Hajj and Diane Mourad performed the research and wrote the article; May Ghossoub, Antoine Geagea, Halim Abboud, and Philippe Saniour included the patients and performed the clinical assessment; Souheil Hallit collected and analyzed the data; Lydia Rabbaa Khabbaz contributed to the design of the study and supervised the whole project. The Journal of Nervous and Mental Disease: October 2019 - Volume 207 - Issue 10 - p 847-853 doi: 10.1097/NMD.0000000000001033 Buy Metrics Abstract The objective was to uncover demographical and clinical factors associated with migraine and irritable bowel syndrome (IBS) in a group of patients experiencing both painful disorders and to identify their triggering factors. A prospective study was performed between January 2016 and June 2017. Clinical characteristics and potential generating factors for both pathologies were then assessed using validated questionnaires. Our study showed that the percentage of patients diagnosed with migraine and having IBS was 34.3%. Compared with patients with migraine alone, patients having both diseases were identified with higher prevalence of concomitant chronic/psychiatric diseases, lower frequency of migraine attacks, and lower prevalence of throbbing/distressing/enervating pain and concentration difficulties than patients with migraine alone. Moreover, patients in this subgroup had moderate abdominal pain intensity, and constipation was the predominant stool type. Finally, some dietary and environmental factors seem to be significantly important triggering factors of migraine/IBS pain. Copyright © 2019 Wolters Kluwer Health, Inc. All rights reserved.