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Impact of Sleep Disorders and Other Factors on the Quality of Life in General Population

A Cross-Sectional Study

Hallit, Souheil, PharmD, MSc, MPH, PhD*†; Hajj, Aline, PharmD, PhD‡§; Sacre, Hala, PharmD†∥; Al Karaki, Gloria, MD*; Malaeb, Diana, PharmD, MPH¶#; Kheir, Nelly, MSc**; Salameh, Pascale, PharmD, MPH, PhD†††‡‡; Hallit, Rabih, MD*

The Journal of Nervous and Mental Disease: May 2019 - Volume 207 - Issue 5 - p 333–339
doi: 10.1097/NMD.0000000000000968
Original Articles

The study objective was to assess if insomnia, along with other factors, can impact the physical and mental quality of life (QOL) of the Lebanese general population. This cross-sectional study, conducted between November 2017 and March 2018, enrolled 756 community-dwelling participants. A first linear regression, using the SF-12 PCS score as the dependent variable, showed that having a family history of insomnia problems (β = 1.107, p = 0.026) was significantly associated with higher physical QOL (higher SF-12 PCS score), whereas increased stress (β = 0.048, p = 0.015) was significantly associated with lower physical QOL. A second linear regression, using the SF-12 MCS score as dependent variable, showed that having increased age (β = −0.079, p < 0.001) was significantly associated with lower mental QOL. Despite its cross-sectional design and the modest sample size, this study adds to the evidence that insomnia, along with other factors (including sociodemographic and psychological factors), can have a detrimental impact on both physical and mental QOL of participants.

*Faculty of Medicine and Medical Sciences, Holy Spirit University of Kaslik (USEK), Jounieh;

INSPECT-LB: Institut National de Santé Publique, Epidémiologie Clinique et Toxicologie–Liban;

Faculty of Pharmacy, Saint-Joseph University;

§Laboratoire de Pharmacologie, Pharmacie Clinique et Contrôle de Qualité des Médicaments, Saint-Joseph University;

Drug Information Center, Order of Pharmacists in Lebanon;

School of Pharmacy, Lebanese International University, Beirut;

#Department of Life and Science, Paris Est University, Paris;

**Faculty of Pedagogy, Université de la Sainte Famille, Batroun; and

††Faculty of Medicine, and

‡‡Faculty of Pharmacy, Lebanese University, Beirut, Lebanon.

Souheil Hallit and Aline Hajj are first coauthors; Pascale Salameh and Rabih Hallit are last coauthors.

Send reprint requests to Souheil Hallit, PharmD, MSc, MPH, PhD, Bldg 560, St 8, 1st floor, Biakout, Lebanon. E-mail:

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