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Prevalence of Obsessive-Compulsive Disorder in Patients With Schizophrenia and Outcome on Positive and Negative Symptoms, Cognition, and Quality of Life

Wehbé, Joelle, MSc*; Haddad, Chadia, MPH; Obeid, Sahar, PhD†‡§; Hallit, Souheil, PharmD, MSc, MPH, PhD∥¶; Haddad, Georges, MD*†∥

The Journal of Nervous and Mental Disease: April 2019 - Volume 207 - Issue 4 - p 239–245
doi: 10.1097/NMD.0000000000000956
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The objectives were to examine the prevalence of obsessive-compulsive disorder (OCD) in hospitalized patients with schizophrenia and to compare the clinical, cognitive, and functional characteristics of schizophrenia patients with and without OCD. This cross-sectional study, performed between May and August 2018, enrolled 308 patients (200 men and 108 women). The prevalence of OCD in patients with schizophrenia was 3.2%. An increase in patients having a mild β was significantly associated with higher social relationship score (β = 1.68) and the Memory Functioning Scale–Informant (MFS-I) version (β = 5.67). OCD did not affect the positive and negative symptoms of these patients. The prevalence of OCD in these patients was low (3.2%). Schizophrenia patients with and without OCD have comparable clinical profiles with few exceptions. The existence of OCD may affect the social relationship quality of life and the MFS-I version.

*Faculty of Sciences, Lebanese University, Fanar;

Psychiatric Hospital of the Cross, Jal Eddib;

Faculty of Philosophy and Human Sciences, Holy Spirit University, Kaslik;

§Faculty of Pedagogy, Lebanese University, Beirut;

Faculty of Medicine and Medical Sciences, Holy Spirit University of Kaslik (USEK), Jounieh; and

INSPECT-LB: Institut National de Sante Publique, Epidemiologie Clinique et Toxicologie, Beirut, Lebanon.

Souheil Hallit and Georges Haddad are the last co-authors.

Send reprint requests to Souheil Hallit, PharmD, MSc, MPH, PhD, St 8, Bldg 560, 1st Floor, Biakout, Lebanon. E-mail: souheilhallit@hotmail.com; Georges Haddad, MD, Psychiatric Hospital of the Cross, PO Box 60096, Jall-Eddib, Lebanon. E-mail: georgeshaddaddad.hpc@gmail.com.

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