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Personality Traits in Panic Disorder Patients With and Without Comorbidities

Zugliani, Morena M. MD*; Martin-Santos, Rocio MD, PhD†‡; Nardi, Antonio Egidio MD, PhD*; Freire, Rafael Christophe MD, PhD*

The Journal of Nervous and Mental Disease: November 2017 - Volume 205 - Issue 11 - p 855–858
doi: 10.1097/NMD.0000000000000745
Original Articles

Panic disorder (PD) is often correlated with high neuroticism and low extraversion. This study aims to ascertain whether PD patients differ from healthy controls in regard to personality traits and determine if these traits are correlated with comorbid disorders, anxiety, and depression symptoms. Personality traits of 69 PD patients and 42 controls were compared using the Maudsley Personality Inventory. In PD patients, comorbidities, anxiety, and depression symptoms were also evaluated. PD patients showed higher neuroticism and lower extraversion compared with healthy controls. Patients without comorbidities presented similar results to controls, whereas those with comorbidities presented higher neuroticism and lower extraversion scores. PD per se may be unrelated to deviant personality traits, although comorbidities with major depressive disorder and agoraphobia are probably associated with high neuroticism and low extraversion. These traits show a strong correlation with the accumulation and severity of these disorders.

*Laboratory of Panic and Respiration, Institute of Psychiatry, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil; †Psychiatry Department, Hospital Clinic, IDIBAPS, CIBERSAM; and ‡Department of Psychiatry and Clinical Psychobiology, University of Barcelona, Carrer de Villarroel, Barcelona, Spain.

Send reprint requests to Morena M. Zugliani, MD, Rua Doutor Souza Lopes, 07, Botafogo, Rio de Janeiro, Brazil, 22231–060. E-mail:

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