Original ArticlesChronic Low Back Pain Perception and Coping With Pain in the Presence of Psychiatric ComorbidityCiaramella, Antonella MD*; Poli, Paolo MD†Author Information *Aplysia onlus, GIFT Institute of Integrative Medicine; and †Pain Therapy Unit, Azienda Ospedaliero-Universitaria Pisana, Pisa, Italy. Send reprint requests to Antonella Ciaramella, MD, Aplysia onlus, GIFT Institute of Integrative Medicine, p.za Cairoli, 12, 56127 Pisa, Italy. E-mail: firstname.lastname@example.org. The Journal of Nervous and Mental Disease: August 2015 - Volume 203 - Issue 8 - p 632-640 doi: 10.1097/NMD.0000000000000340 Buy Metrics Abstract This retrospective study investigated the influence of psychiatric comorbidity on pain perception and coping with pain in tertiary pain clinic patients, 427 treated for chronic low back pain (CLBP) and 629 for other forms of chronic pain (CG). No differences in psychosomatic dimensions were found between the two groups, but Italian Pain Questionnaire dimensions and intensity scores (t = 7.35; p < 0.0001) were higher in CLBP than in CG subjects. According to the Mini-International Neuropsychiatric Interview, CLBP patients also had a higher prevalence of lifetime major depressive episodes (χ2 = 4.96; p < 0.05), dysthymic disorder (χ2 = 4.64; p < 0.05), suicide risk (χ2 = 10.43; p < 0.01), and agoraphobia (χ2 = 6.31; p < 0.05) than CG patients did. The Multidimensional Pain Inventory showed a close association between CLBP and both agoraphobia (χ2 = 3.74; p < 0.05) and dysfunctional coping style (χ2 = 8.25; p < 0.01), which increased disability. Both agoraphobia and lifetime depression were associated with an overall increase in dimensions and pain intensity in CLBP, but not in CG. Copyright © 2015 Wolters Kluwer Health, Inc. All rights reserved.