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Self-Efficacy and Quality of Life Among People With Bipolar Disorder

Abraham, Kristen M. PhD*†; Miller, Christopher J. PhD‡§; Birgenheir, Denis G. PhD†∥; Lai, Zongshan MPH†∥; Kilbourne, Amy M. PhD, MPH†∥

The Journal of Nervous and Mental Disease: August 2014 - Volume 202 - Issue 8 - p 583–588
doi: 10.1097/NMD.0000000000000165
Original Articles

People with bipolar disorders report a lower quality of life than the general population does, and few mutable factors associated with health-related quality of life (HRQoL) among people with bipolar disorders have been identified. Using a cross-sectional design, these analyses examined whether self-efficacy was associated with mental and physical HRQoL in a sample of 141 patients with bipolar disorder who completed baseline assessments for two randomized controlled trials. Multiple linear regression analyses indicated that higher levels of self-efficacy were associated with higher mental and physical HRQoL, after controlling for demographic factors and clinical factors (including mood symptoms, comorbid medical conditions, and substance use). Future research should examine whether targeted treatments that aim to improve self-efficacy (such as self-management interventions) lead to improvements in HRQoL among people with bipolar disorder and other serious mental illnesses.

*Department of Psychology, University of Detroit Mercy, Detroit, MI; †VA Serious Mental Illness Treatment Resource and Evaluation Center, Center for Clinical Management Research, Ann Arbor, MI; ‡Center for Organization, Leadership, and Management Research, VA Boston Healthcare System, Boston, MA; §Department of Psychiatry, Harvard Medical School, Boston, MA; and ∥Department of Psychiatry, University of Michigan Medical School, Ann Arbor, MI.

Send reprint requests to Kristen M. Abraham, PhD, VA Serious Mental Illness Treatment Resource and Evaluation Center, 2800 Plymouth Road, Building 16 Floor 2, Ann Arbor, MI 48109-2800. E-mail:

© 2014 by Lippincott Williams & Wilkins